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Valerie L Jacobs Selected Research

propentofylline

8/2013Increased glutamate uptake in astrocytes via propentofylline results in increased tumor cell apoptosis using the CNS-1 glioma model.
4/2012Propentofylline, a CNS glial modulator does not decrease pain in post-herpetic neuralgia patients: in vitro evidence for differential responses in human and rodent microglia and macrophages.
2/2012Propentofylline decreases tumor growth in a rodent model of glioblastoma multiforme by a direct mechanism on microglia.
1/2012Propentofylline targets TROY, a novel microglial signaling pathway.

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Valerie L Jacobs Research Topics

Disease

5Neoplasms (Cancer)
08/2013 - 01/2011
3Glioma (Gliomas)
08/2013 - 01/2012
2Glioblastoma (Glioblastoma Multiforme)
02/2012 - 01/2012
1Neuralgia (Stump Neuralgia)
04/2012
1Pain (Aches)
04/2012
1Brain Neoplasms (Brain Tumor)
01/2012
1Vitiligo
01/2011

Drug/Important Bio-Agent (IBA)

4propentofyllineIBA
08/2013 - 01/2012
2methylxanthineIBA
02/2012 - 01/2012
1Glutamic Acid (Glutamate)FDA Link
08/2013
1Pharmaceutical PreparationsIBA
08/2013
1protoporphyrin IXIBA
01/2012
1AntigensIBA
01/2011
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
01/2011
1GlucocorticoidsIBA
01/2011

Therapy/Procedure

2Therapeutics
01/2012 - 01/2011
1Injections
02/2012